Active B forms13 botanicalsMethyl+

Daily foundation · Methylation & cellular repair

Methyl+

A comprehensive multivitamin with active-form B vitamins and patented DeltaGold tocotrienols.

  • Active-form methylated B vitamins for optimal methylation support.*
  • DeltaGold tocotrienols for superior antioxidant and cardiovascular protection.*
  • Bioavailable citrate and aspartate mineral forms for optimal absorption.
  • 400mg phytonutrient blend supporting cellular defense and metabolic health.*
  • Therapeutic B-complex dosing. Calibrated for energy production, neurotransmitter synthesis, and DNA repair.

Coming soon

Not available just yet.

This formula is in production. Leave your email and we will let you know the day it is ready.

Bloodwork panels are available now.

Why it matters

Why take Methyl+

Methylation is a hand-off your body runs billions of times a day, switching on energy production, mood chemistry and repair. B vitamins are the raw material, but many multivitamins use forms your body has to convert first.

Ready to use

Active B12 and folate your body can use directly, whether or not you carry an MTHFR variant.

Energy and mood

B vitamins support energy production and the chemistry behind mood and focus.*

Cell protection

DeltaGold tocotrienols, a form of vitamin E, support your cells’ antioxidant defenses.*

Beyond the basics

A 400mg blend of 13 standardized plant extracts rounds out a complete daily multivitamin.

The evidence

Active forms, because conversion is the bottleneck.

13 standardized plant extractsIn a 400mg phytonutrient blend, alongside active B vitamins
  1. Active forms

    Methylcobalamin and BioFolate are B12 and folate your body can use directly, whatever your MTHFR status.

  2. DeltaGold vitamin E

    A patented tocotrienol complex from annatto that supports your cells’ antioxidant defenses.*

  3. Minerals that absorb

    Citrate and aspartate mineral forms throughout, chosen for how well they absorb.

Read the full research summary
Methyl+ is built around bioavailability. Methylcobalamin and BioFolate deliver active-form B12 and folate the body can use directly, regardless of MTHFR gene status. Methylation governs DNA repair, neurotransmitter synthesis, gene expression, and detoxification, processes that depend on nutrients being in their active, usable form.

The vitamin E in Methyl+ is DeltaGold, a patented tocotrienol complex derived from the annatto plant, containing 90% delta and 10% gamma tocotrienols. Clinical research demonstrates greater antioxidant activity and cardiovascular protection compared to standard alpha-tocopherol.

Minerals are provided in citrate and aspartate forms throughout. The 400mg phytonutrient blend features 13 standardized botanical extracts, including green tea EGCG, pomegranate, resveratrol, grape seed, and blueberry anthocyanins.

Questions

Good to know.

What is methylation, simply?

It's a chemical hand-off your body performs billions of times a day, adding a small "methyl" tag to molecules to switch processes on and off, from energy production to mood and detox. B-vitamins are the raw material that keeps it running.

Do I need the MTHFR test first?

It's helpful but not required. Methyl+ uses active forms that work whether or not you carry a variant. The test simply tells you how much you stand to benefit, so you can prioritise with confidence.

When should I take it?

In the morning, with or without food. B-vitamins support energy, so taking them early avoids interfering with sleep.

Could it feel overstimulating?

Most people feel steady, clean energy. A small number are sensitive to active B-vitamins, if that's you, take it earlier in the day or every other day to start.

The Rethryv Program

Ready for the whole picture?

Six months with one physician-led team. We start with your bloodwork, bring in everything about how you live, build your personalized Longevity Blueprint and guide you through it every day.

  1. 01Your bloodwork
  2. 02Your daily data
  3. 03Your Blueprint
  4. 04Guided every day
Explore the Program

Starting at $299/mo