Diagnostics · One-time test
MTHFR Genetic
How your body processes folate and B vitamins. Informs your supplementation for life. Pairs with Methyl+.
- Free physician review call included
- A one-time genetic test that informs your plan for life
- Drawn at an accredited Quest location near you
Why it matters
Metabolic decline is quiet — until it isn't.
Folate, activated
MTHFR builds the enzyme that turns folate into the active form your body can actually use to run methylation.
A common variant
A large share of people carry a variant that slows this step, often for years without ever knowing.
Changes what you take
If you're affected, methylated B-vitamins, not ordinary folic acid, are what make the difference.
What we measure
Every marker, in four systems.
Variants analyzed 2
What it informs 4
Every panel includes a live 1-on-1 review call.
About 10 to 12 days after your draw, a Rethryv physician sits down with you, on video, and reads your results together. What's strong, what to watch, and exactly what to do next. It's included free, and it's the part most people remember.
How it works
A service, handled end to end.
Order online
Check out in a minute. Add other panels to combine them into a single draw.
We reach out to schedule
Within about one business day, we book both appointments together so nothing slips: your draw and your review call.
Blood draw at Quest
A quick, fasted draw at an accredited Quest location near you.
Physician review call
About 10 to 12 days later, your doctor walks through every result and your personalized next steps.
Included freeQuestions
Good to know.
Is this like a 23andMe report?
No. This is a focused clinical test of the two MTHFR variants that actually matter for methylation, read and explained by a physician, not a raw data dump you're left to interpret alone.
Will I ever need to retest?
Never. Your genes don't change, so this is genuinely a one-time test. The result is yours for life.
Do I need to fast?
No fasting required for a genetic test. If you combine it with a blood panel that does need fasting, we'll send clear instructions.
What will I actually do with the result?
It tells you whether to choose methylated B-vitamins like Methyl+ over ordinary folic acid, and it informs how you manage homocysteine over time.
Is my genetic data private?
Yes. Your result is handled confidentially and never sold. It exists to guide your care, full stop.